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Cellosaurus MCF7(Cas9) (CVCL_E7J9)

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Cell line name MCF7(Cas9)
Accession CVCL_E7J9
Resource Identification Initiative To cite this cell line use: MCF7(Cas9) (RRID:CVCL_E7J9)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0031 (MCF-7)
Sex of cell Female
Age at sampling 69Y
Category Cancer cell line
Web pages Provider; BRICS; ECC3035; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3969
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1