Cellosaurus cell line COLO 205(Cas9) (CVCL

Entry history
Cell line name	COLO 205(Cas9)
Accession	CVCL_E7J3
Resource Identification Initiative	To cite this cell line use: COLO 205(Cas9) (RRID:CVCL_E7J3)
Comments	Population: Caucasian. Genetic integration: Method=Transduction; Gene=UniProtKB; Q99ZW2; Streptomyces pyogenes Cas9. Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Thr1556Asnfs3 (c.4666dupA) (c.4666_4667insA); ClinVar=VCV000428112; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Asn287Ser (c.860A>G); ClinVar=VCV000133954; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr103fs37 (c.308_321delTGTGTAACAGTTCC); Zygosity=Homozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0218 (COLO 205)
Sex of cell	Male
Age at sampling	70Y
Category	Cancer cell line
Web pages	Provider; BRICS; ECC3017; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3951
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1