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Cellosaurus UG5LN (CVCL_E7IT)

[Text version]
Cell line name UG5LN
Accession CVCL_E7IT
Resource Identification Initiative To cite this cell line use: UG5LN (RRID:CVCL_E7IT)
Comments Population: Caucasian.
Characteristics: Negative control cell line for measurement of nuclear receptor activity. Transfected with a (GAL4RE)5-betaGlobin-Luc-SV40-Neo construct where expression of the luciferase gene is driven by a pentamer of yeast activator GAL4-binding sites in front of beta-globin promoter (Inserm Transfert=RT00625).
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Firefly luciferase.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Children:
CVCL_E7IU (UG5LN GAL4-hMR)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Web pages Provider; Inserm Transfert; RT00625; https://technology-offers.inserm-transfert.com/offer/ug5ln-cell-line/
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1