Cellosaurus cell line M2-2 (CVCL

Cellosaurus M2-2 (CVCL_E7IN)

Cross-references
Cell line name	M2-2
Accession	CVCL_E7IN
Resource Identification Initiative	To cite this cell line use: M2-2 (RRID:CVCL_E7IN)
Comments	Characteristics: Has a sarcomatoid morphology (PNsarc); hypoxia high subcategory (PNsarc2) (PubMed=27129173; PubMed=32290283). Doubling time: 65 hours (PubMed=27129173). Transformant: ChEBI; CHEBI_46666; Crocidolite asbestos. Omics: Proteomics. Derived from site: In situ; Ascites; UBERON=UBERON_0007795. Cell type: Mesothelial cell; CL=CL_0000077.
Species of origin	Rattus norvegicus (Rat) (NCBI Taxonomy: 10116) Breed/subspecies: Fischer 344; RS=RS_0000215.
Sex of cell	Male
Category	Transformed cell line
Web pages	Provider; Inserm Transfert; RT00426; https://technology-offers.inserm-transfert.com/offer/rat-mesothelial-cell-line-m2-2/
Publications	PubMed=27129173; DOI=10.18632/oncotarget.8970; PMCID=PMC5085183 David Roulois, Sophie Deshayes, Marie-Noelle Guilly, Joelle S. Nader, Charly Liddell, Myriam Robard, Philippe Hulin, Amal Ouacher, Vanessa Le Martelot, Jean-Francois Fonteneau, Marc Gregoire ...Show all 13 authors... , Christophe Blanquart, Daniel Loic Pouliquen; Show fewer authors Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine. Oncotarget 7:34664-34687(2016) PubMed=32290283; DOI=10.3390/cancers12040939; PMCID=PMC7226589 Joelle S. Nader, Jordan Guillon, Coralie Petit, Alice Boissard, Florence Franconi, Stephanie Blandin, Sylvia Lambot, Marc Gregoire, Veronique Verriele-Beurrier, Beatrice Nawrocki-Raby, Philippe Birembaut ...Show all 14 authors... , Olivier Coqueret, Catherine Guette, Daniel Loic Pouliquen; Show fewer authors S100A4 is a biomarker of tumorigenesis, EMT, invasion, and colonization of host organs in experimental malignant mesothelioma. Cancers (Basel) 12:939.1-939.18(2020)
Proteomic databases	PRIDE; PXD060521
Entry history
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1