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Cellosaurus B5BC CL (CVCL_E7HT)

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Cell line name B5BC CL
Accession CVCL_E7HT
Resource Identification Initiative To cite this cell line use: B5BC CL (RRID:CVCL_E7HT)
Comments Characteristics: Tumorigenic. Will induce tumors when injected subcutaneously in the mammary fat pad of immunocompetent tumor-naive C57BL/6 mice (PubMed=37344100).
Transformant: ChEBI; CHEBI_6716; Medroxyprogesterone acetate (MPA).
Transformant: ChEBI; CHEBI_254496; 7,12-dimethyltetraphene (DMBA; dimethylbenzanthracene).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Disease Malignant neoplasms of the mouse mammary gland (NCIt: C21678)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Sex of cell Female
Age at sampling 13-16W
Category Cancer cell line
Publications

PubMed=37344100; DOI=10.1136/jitc-2023-007117; PMCID=PMC10314679
Maria Perez-Lanzon, Vincent Carbonnier, Pierre Cordier, Fatima Domenica Elisa De Palma, Adriana Petrazzuolo, Christophe Klein, Floriane Arbaretaz, Khady Mangane, Gautier Stoll, Isabelle Martins, Helene Fohrer-Ting ...Show all 22 authors... , Juliette Paillet, Sophie Mouillet-Richard, Delphine Le Corre, Wen-Jin Xiao, Marine Sroussi, Chantal Desdouets, Pierre Laurent-Puig, Jonathan G. Pol, Carlos Lopez-Otin, Maria Chiara Maiuri, Guido Kroemer; Show fewer authors
New hormone receptor-positive breast cancer mouse cell line mimicking the immune microenvironment of anti-PD-1 resistant mammary carcinoma.
J. Immunother. Cancer 11:e007117.1-e007117.17(2023)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1