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Cellosaurus SFCI-SCC-09ko+Tg (CVCL_E7HD)

[Text version]
Cell line name SFCI-SCC-09ko+Tg
Accession CVCL_E7HD
Resource Identification Initiative To cite this cell line use: SFCI-SCC-09ko+Tg (RRID:CVCL_E7HD)
Comments Population: Caucasian.
Characteristics: Using CRISPR/Cas9 FANCA was introduced at the chromosome 4 SHS231 safe locus (OHSU).
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:3582; FANCA.
Genetic integration: Method=CRISPR/Cas9; Gene=HGNC; HGNC:3582; FANCA.
Derived from site: In situ; Oral cavity, tongue, anterior part; UBERON=UBERON_0010032.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys275Glyfs*20 (c.822_853del); Zygosity=Homozygous (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E7HC (SFCI-SCC-09ko)
Sex of cell Male
Age at sampling 25Y
Category Cancer cell line
STR profile Source(s): OHSU

Markers:
AmelogeninX,Y
CSF1PO11
D5S81812
D7S8208
D13S3179
D16S53910,11
TH018,9
TPOX9,11
vWA17

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Web pages Provider; OHSU; -; https://apps.ohsu.edu/research/fanconi-anemia/uploads/material_datasheet/cell_line/download/sfci-scc-09-6222a9d4f3797875140876.pdf
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1