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Cellosaurus HPM clone #4 (CVCL_E7FX)

[Text version]
Cell line name HPM clone #4
Synonyms HP proMastocyte clone #4
Accession CVCL_E7FX
Resource Identification Initiative To cite this cell line use: HPM clone #4 (RRID:CVCL_E7FX)
Comments Doubling time: 3-4 days (DOI=10.1016/j.jaci.2012.12.1081; PubMed=27459687).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: Mast cell; CL=CL_0000097.
Sequence variations
Disease Hermansky-Pudlak syndrome 1 (NCIt: C150367)
Hermansky-Pudlak syndrome with pulmonary fibrosis (ORDO: Orphanet_231500)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E7FY (HPM clone #4-HPS1)
Originate from same individual CVCL_E7FW ! HPM clone #3
Sex of cell Male
Age at sampling 24-47Y
Category Spontaneously immortalized cell line
Publications

DOI=10.1016/j.jaci.2012.12.1081
Kirshenbaum A.S., Desai A., Bandara G., Cruse G., Fischer E.R., Gilfillan A.M., Gahl W.A., Metcalfe D.D.
Establishment of the Hermansky Pudlak mastocyte (HPM) cell line which has the HPS1 16-bp duplication (c.1470_1486dup16).
J. Allergy Clin. Immunol. 131 Suppl. 2:AB115-AB115(2013)

PubMed=27459687; DOI=10.1371/journal.pone.0159177; PMCID=PMC4961407
Kirshenbaum A.S., Cruse G., Desai A., Bandara G., Leerkes M.R., Lee C.-C.R., Fischer E.R., O'Brien K.J., Gochuico B.R., Stone K.D., Gahl W.A., Metcalfe D.D.
Immunophenotypic and ultrastructural analysis of mast cells in Hermansky-Pudlak syndrome type-1: a possible connection to pulmonary fibrosis.
PLoS ONE 11:e0159177.1-e0159177.23(2016)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1