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Cellosaurus ESCC-DRtca2 (CVCL_E7ES)

[Text version]
Cell line name ESCC-DRtca2
Accession CVCL_E7ES
Resource Identification Initiative To cite this cell line use: ESCC-DRtca2 (RRID:CVCL_E7ES)
Comments Characteristics: High malignancy. Induced by continuous stimulation with 2 mM of taurocholic acid (TCA) stimulation for 2 months (PubMed=24551170).
Omics: Variations; Array-based CGH.
Derived from site: Metastatic; Thorax; UBERON=UBERON_0000915.
Disease Squamous cell carcinoma of the rat esophagus (NCIt: C63892)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar; RS=RS_0000955.
Hierarchy Parent: CVCL_R804 (ESCC-DR)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=24551170; DOI=10.1371/journal.pone.0088831; PMCID=PMC3925151
Sho Sato, Hiroto Yamamoto, Ken-ichi Mukaisho, Shota Saito, Takanori Hattori, Gaku Yamamoto, Hiroyuki Sugihara;
Continuous taurocholic acid exposure promotes esophageal squamous cell carcinoma progression due to reduced cell loss resulting from enhanced vascular development.
PLoS ONE 9:e88831.1-e88831.9(2014)

PubMed=31215094; DOI=10.1111/cas.14105; PMCID=PMC6676276
Masayoshi Munemoto, Ken-ichi Mukaisho, Tomoharu Miyashita, Katsunobu Oyama, Yusuke Haba, Koichi Okamoto, Jun Kinoshita, Itasu Ninomiya, Sachio Fushida, Naoko Taniura, Hiroyuki Sugihara, Takashi Fujimura;
Roles of the hexosamine biosynthetic pathway and pentose phosphate pathway in bile acid-induced cancer development.
Cancer Sci. 110:2408-2420(2019)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1