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Cellosaurus ESCC-DRtca2 (CVCL_E7ES)

[Text version]
Cell line name ESCC-DRtca2
Accession CVCL_E7ES
Resource Identification Initiative To cite this cell line use: ESCC-DRtca2 (RRID:CVCL_E7ES)
Comments Characteristics: High malignancy. Induced by continuous stimulation with 2 mM of taurocholic acid (TCA) stimulation for 2 months (PubMed=24551170).
Omics: Variations; Array-based CGH.
Derived from site: Metastatic; Thorax; UBERON=UBERON_0000915.
Disease Squamous cell carcinoma of the rat esophagus (NCIt: C63892)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar; RS=RS_0000955.
Hierarchy Parent: CVCL_R804 (ESCC-DR)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=24551170; DOI=10.1371/journal.pone.0088831; PMCID=PMC3925151
Sato S., Yamamoto H., Mukaisho K.-i., Saito S., Hattori T., Yamamoto G., Sugihara H.
Continuous taurocholic acid exposure promotes esophageal squamous cell carcinoma progression due to reduced cell loss resulting from enhanced vascular development.
PLoS ONE 9:e88831.1-e88831.9(2014)

PubMed=31215094; DOI=10.1111/cas.14105; PMCID=PMC6676276
Munemoto M., Mukaisho K.-i., Miyashita T., Oyama K., Haba Y., Okamoto K., Kinoshita J., Ninomiya I., Fushida S., Taniura N., Sugihara H., Fujimura T.
Roles of the hexosamine biosynthetic pathway and pentose phosphate pathway in bile acid-induced cancer development.
Cancer Sci. 110:2408-2420(2019)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1