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Cellosaurus iRBMSCs (CVCL_E7CC)

[Text version]
Cell line name iRBMSCs
Synonyms immortalized Rabbit Bone Marrow Mesenchymal Stem Cells
Accession CVCL_E7CC
Resource Identification Initiative To cite this cell line use: iRBMSCs (RRID:CVCL_E7CC)
Comments Characteristics: Transduced with a SSR#41 vector (LTR-FRT-HygR-HSV1-TK-IRES-SV40LT-FRT-Neo-LTR) that allows removal of the SV40 TAg by using FLP (PubMed=39592420).
Genetic integration: Method=Transduction; Gene=UniProtKB; Q9QNF7; Human herpesvirus 1 TK.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Mesenchymal stem cell of bone marrow; CL=CL_0002540.
Species of origin Oryctolagus cuniculus (Rabbit) (NCBI Taxonomy: 9986)
Breed/subspecies: New Zealand white; VBO=VBO_0001267.
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Conditionally immortalized cell line
Publications

PubMed=39592420; DOI=10.1002/ame2.12513; PMCID=PMC11680476
Zhang Y., Xu C., Huang Y., Tan D.-M., Luo W.-P., Zhang Y., Tan Y.
Establishment of immortalized rabbit bone marrow mesenchymal stem cells and a preliminary study of their osteogenic differentiation capability.
Animal Models Exp. Med. 7:824-834(2024)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1