Cellosaurus cell line JCF-4 (CVCL

Entry history
Cell line name	JCF-4
Accession	CVCL_E7AX
Resource Identification Initiative	To cite this cell line use: JCF-4 (RRID:CVCL_E7AX)
Comments	Population: Japanese. Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:1884; CFTR; Simple; p.Val470Glufs*54 (c.1409_1418del); ClinVar=VCV000053250; Zygosity=Homozygous (DOI=10.1016/j.gendis.2024.101506).
Disease	Cystic fibrosis (NCIt: C2975) Cystic fibrosis (ORDO: Orphanet_586)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_J695 (CF1TKB)
Sex of cell	Male
Age at sampling	13Y
Category	Induced pluripotent stem cell
Publications	DOI=10.1016/j.gendis.2024.101506 Okumura H., Hayashi M., Yamashita H., Hattori F. Establishment and characterization of an induced pluripotent stem cell line from a Japanese cystic fibrosis patient with homozygous 1540del10 CFTR mutation. Genes Dis. 0:0-0(2025)
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1