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Cellosaurus FiPS Ctrl1-SV4F-7 NF1_C (CVCL_E7AH)

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Cell line name FiPS Ctrl1-SV4F-7 NF1_C
Synonyms NF1C-FiPS-SV4F7; NF1_C; NF1(-/-) edited FiPS Ctrl1-SV4F-7
Accession CVCL_E7AH
Resource Identification Initiative To cite this cell line use: FiPS Ctrl1-SV4F-7 NF1_C (RRID:CVCL_E7AH)
Comments Part of: Spanish Stem Cell Bank (Banco Nacional de Lineas Celulares) collection.
From: Institut d'Investigacio Germans Trias i Pujol (IGTP); Barcelona; Spain.
Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:7765; NF1.
Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471.
Cell type: Fibroblast of foreskin; CL=CL_1001608.
Disease Neurofibromatosis type 1 (NCIt: C3273)
Neurofibromatosis type 1 (ORDO: Orphanet_636)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_9S19 (ESi044-C)
Sex of cell Male
Age at sampling 9Y
Category Induced pluripotent stem cell
Web pages Provider; BNLC; -; https://www.isciii.es/documents/20119/880364/Caracteristicas+-+NF1%28--%29+edited+FiPS+Ctrl1-SV4F-7+Solicitud+de+dep%C3%B3sito.pdf
Publications

PubMed=35172160; DOI=10.1016/j.celrep.2022.110385
Helena Mazuelas, Miriam Magallon-Lorenz, Juana Fernandez-Rodriguez, Itziar Uriarte-Arrazola, Yvonne Richaud-Patin, Ernest Terribas, Alberto Villanueva, Elisabeth Castellanos, Ignacio Blanco, Angel Raya, Jakub Chojnacki ...Show all 17 authors... , Holger Heyn, Cleofe Romagosa, Conxi Lazaro, Bernat Gel, Meritxell Carrio, Eduard Serra; Show fewer authors
Modeling iPSC-derived human neurofibroma-like tumors in mice uncovers the heterogeneity of Schwann cells within plexiform neurofibromas.
Cell Rep. 38:110385.1-110385.15(2022)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1