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Cellosaurus U2OS-FGFR1-K514R (CVCL_E7A6)

[Text version]
Cell line name U2OS-FGFR1-K514R
Accession CVCL_E7A6
Resource Identification Initiative To cite this cell line use: U2OS-FGFR1-K514R (RRID:CVCL_E7A6)
Comments Population: Caucasian.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3688; FGFR1 (Note=With p.Lys514Arg).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Web pages Provider; I2B; P-98; http://inven2biologics.com/shop/cell-lines/human/u2os-fgfr1-k514r-osteosarcoma-cell-line
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1