Cellosaurus cell line MCF7-FGFR4 (CVCL

Entry history
Cell line name	MCF7-FGFR4
Synonyms	MCF7-R4
Accession	CVCL_E6ZX
Resource Identification Initiative	To cite this cell line use: MCF7-FGFR4 (RRID:CVCL_E6ZX)
Comments	Population: Caucasian. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3691; FGFR4. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
Disease	Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0031 (MCF-7)
Sex of cell	Female
Age at sampling	69Y
Category	Cancer cell line
Web pages	Provider; I2B; P-99; http://inven2biologics.com/shop/cell-lines/human/mcf7-fgfr4-breast-cancer-cell-line
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1