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Cellosaurus U2OS-AP3#19 (CVCL_E6ZU)

[Text version]
Cell line name U2OS-AP3#19
Synonyms U2OS-AP3 clone 19
Accession CVCL_E6ZU
Resource Identification Initiative To cite this cell line use: U2OS-AP3#19 (RRID:CVCL_E6ZU)
Comments Population: Caucasian.
Virology: The parent cell line which contains chromosomally integrated human herpesvirus 6A (ciHHV-6A) was surinfected with HHV-6B. The resulting cell line contains an average of 2.9 HHV-6A and 2.2 HHV-6B genomes/cell (PubMed=28468878).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; HGNC:9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E6ZT (U2OS-AP3)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line
Publications

PubMed=28468878; DOI=10.1128/JVI.00437-17; PMCID=PMC5487542
Gravel A., Dubuc I., Wallaschek N., Gilbert-Girard S., Collin V., Hall-Sedlak R., Jerome K.R., Mori Y., Carbonneau J., Boivin G., Kaufer B.B., Flamand L.
Cell culture systems to study human herpesvirus 6A/B chromosomal integration.
J. Virol. 91:e00437.17.1-e00437.17.14(2017)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1