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Cellosaurus A549 fat-1 (CVCL_E6ZC)

[Text version]
Cell line name A549 fat-1
Synonyms f-A549
Accession CVCL_E6ZC
Resource Identification Initiative To cite this cell line use: A549 fat-1 (RRID:CVCL_E6ZC)
Comments Population: Caucasian.
Characteristics: Applicable for studies investigating the effects of endogenous omega3-polyunsaturated fatty acids (ABM=T6262).
Doubling time: 18-26 hours (ABM=T6262).
Genetic integration: Method=Transfection; Gene=UniProtKB; Q9NEQ0; Caenorhabditis elegans omega-3 fatty acid desaturase fat-1.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Derived from site: In situ; Lung; UBERON=UBERON_0002048.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Ser (c.34G>A); ClinVar=VCV000012584; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11389; STK11; Simple; p.Gln37Ter (c.109C>T); ClinVar=VCV000376334; Zygosity=Homozygous (from parent cell line).
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0023 (A-549)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

DOI=10.1158/1538-7445.AM2016-4651
Jeong S., Jing K.-P., Shin S., Kim S., Jeon Y.-J., Heo J.-Y., Kweon G.R., Park S.-K., Park J.-I., Lim K.
Docosahexaenoic acid-induced degradation of epidermal growth factor receptor through lysosome and ubiquitin/proteasomal system in human non-small cell lung cancer cells.
Cancer Res. 76 Suppl. 14:4651-4651(2016)

Cross-references
Cell line collections (Providers) ABM; T6262
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1