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Cellosaurus PCI (CVCL_E6Z2)

[Text version]
Cell line name PCI
Accession CVCL_E6Z2
Resource Identification Initiative To cite this cell line use: PCI (RRID:CVCL_E6Z2)
Comments Population: African American.
Doubling time: 48-72 hours (ABM=T0412).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Donor information: Established from a patient with bilateral profound sensorineural hearing loss undergoing cochlear implantation (PubMed=37899851).
Derived from site: In situ; Ear, middle ear; UBERON=UBERON_0001756.
Cell type: Epithelial cell; CL=CL_0000066.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 4Y5M
Category Transformed cell line
Publications

PubMed=32433794; DOI=10.1002/lary.28687
Mana Espahbodi, Tina L. Samuels, Caroline McCormick, Pawjai Khampang, Ke Yan, Samuel Marshall, Michael E. McCormick, Robert H. Chun, Steven A. Harvey, David Richard Friedland, Nikki Johnston, Joseph E. Kerschner;
Analysis of inflammatory signaling in human middle ear cell culture models of pediatric otitis media.
Laryngoscope 131:410-416(2021)

PubMed=37899851; DOI=10.1002/lio2.1141; PMCID=PMC10601576
Simon Blaine-Sauer, Tina L. Samuels, Pawjai Khampang, Ke Yan, Michael E. McCormick, Robert H. Chun, Steven A. Harvey, David Richard Friedland, Nikki Johnston, Joseph E. Kerschner;
Establishment of novel immortalized middle ear cell lines as models for otitis media.
Laryngoscope Investig. Otolaryngol. 8:1428-1435(2023)

Cross-references
Cell line collections (Providers) ABM; T0412
Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2