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Cellosaurus CHO-IRLys (CVCL_E6YY)

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Cell line name CHO-IRLys
Accession CVCL_E6YY
Resource Identification Initiative To cite this cell line use: CHO-IRLys (RRID:CVCL_E6YY)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6091; INSR.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_0214 (CHO-K1)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=3101064; DOI=10.1073/pnas.84.3.704; PMCID=PMC304284
Yousuke Ebina, Eiichi Araki, Masato Taira, Fumio Shimada, Masataka Mori, Charles Scott Craik, Kenneth Siddle, Sarah B. Pierce, Richard A. Roth, William J. Rutter;
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity.
Proc. Natl. Acad. Sci. U.S.A. 84:704-708(1987)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1