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Cellosaurus SCCF2-Luc-YFP (CVCL_E6XT)

[Text version]
Cell line name SCCF2-Luc-YFP
Synonyms SCCF2Luc
Accession CVCL_E6XT
Resource Identification Initiative To cite this cell line use: SCCF2-Luc-YFP (RRID:CVCL_E6XT)
Comments Characteristics: Transfected with a luciferase-YFP fusion protein whose expression is under the control of a CMV promoter (PubMed=20959474; PubMed=22265717).
Genetic integration: Method=Transfection; Gene=FPbase; 8DNLG; YFP (Note=EYFP, yellow fluorescent protein derived from GFP).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Oral cavity, gingiva; UBERON=UBERON_0001828.
Disease Feline oral squamous cell carcinoma (NCIt: C132824)
Species of origin Felis catus (Cat) (Felis silvestris catus) (NCBI Taxonomy: 9685)
Hierarchy Parent: CVCL_C4UU (SCCF2)
Sex of cell Male
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=20959474; DOI=10.1158/0008-5472.CAN-10-0850; PMCID=PMC2970642
Chelsea K. Martin, Jillian L. Werbeck, Nanda K. Thudi, Lisa G. Lanigan, Tobie Dianne Wolfe, Ramiro E. Toribio, Thomas John Rosol;
Zoledronic acid reduces bone loss and tumor growth in an orthotopic xenograft model of osteolytic oral squamous cell carcinoma.
Cancer Res. 70:8607-8616(2010)

PubMed=22265717; DOI=10.1016/j.oraloncology.2011.12.012; PMCID=PMC3350825
Chelsea K. Martin, Wessel P. Dirksen, Sherry T. Shu, Jillian L. Werbeck, Nanda K. Thudi, Mamoru Yamaguchi, Tobie Dianne Wolfe, Kristin N. Heller, Thomas John Rosol;
Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma.
Oral Oncol. 48:491-499(2012)

Cross-references
Cell line collections (Providers) ABM; T6447
Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2