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Cellosaurus Genomeditech K-562 H_IL21(Membrane bound) (CVCL_E6W8)

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Cell line name Genomeditech K-562 H_IL21(Membrane bound)
Synonyms Human IL21 (Membrane bound) K-562; H_IL21(Membrane bound) K-562
Accession CVCL_E6W8
Resource Identification Initiative To cite this cell line use: Genomeditech K-562 H_IL21(Membrane bound) (RRID:CVCL_E6W8)
Comments Population: Caucasian.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6005; IL21 (Note=With p.Met1_Asn7del; membrane bound).
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110)
Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0004 (K-562)
Sex of cell Female
Age at sampling 53Y
Category Cancer cell line
Cross-references
Cell line collections (Providers) Genomeditech; GM-C15709
Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2