Cellosaurus cell line Genomeditech K-562 H_IL21(Membrane bound) (CVCL

Cross-references
Cell line name	Genomeditech K-562 H_IL21(Membrane bound)
Synonyms	Human IL21 (Membrane bound) K-562; H_IL21(Membrane bound) K-562
Accession	CVCL_E6W8
Resource Identification Initiative	To cite this cell line use: Genomeditech K-562 H_IL21(Membrane bound) (RRID:CVCL_E6W8)
Comments	Population: Caucasian. Genetic integration: Method=Transduction; Gene=HGNC; HGNC:6005; IL21 (Note=With p.Met1_Asn7del; membrane bound). Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gln136fs*13 (c.406_407insC); Zygosity=Homozygous (from parent cell line).
Disease	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive (NCIt: C9110) Chronic myeloid leukemia (ORDO: Orphanet_521)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0004 (K-562)
Sex of cell	Female
Age at sampling	53Y
Category	Cancer cell line
Cell line collections (Providers)	Genomeditech; GM-C15709
Entry history
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1