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Cellosaurus NCC-GCTB14-C1 (CVCL_E6MP)

[Text version]
Cell line name NCC-GCTB14-C1
Accession CVCL_E6MP
Resource Identification Initiative To cite this cell line use: NCC-GCTB14-C1 (RRID:CVCL_E6MP)
Comments Part of: NCC sarcoma cell line panel.
Population: Japanese.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: 29 hours (PubMed=39604602).
Omics: Phenotyping; Drug screening.
Derived from site: In situ; Bone, left femur; UBERON=UBERON_0000981.
Sequence variations
  • Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Gly35Trp (c.103G>T) (G34W); Zygosity=Heterozygous (PubMed=39604602).
Disease Malignancy in giant cell tumor of bone (NCIt: C4304)
Giant cell tumor of bone (ORDO: Orphanet_363976)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 24Y
Category Cancer cell line
STR profile Source(s): PubMed=39604602

Markers:
AmelogeninX
CSF1PO11,12
D5S81813
D7S82010,12
D13S31710,13
D16S5399,11
D21S1131,32.2
TH016,9
TPOX8,11
vWA17

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Publications

PubMed=39604602; DOI=10.1007/s13577-024-01150-2
Iwata S., Ono T., Noguchi R., Osaki J., Adachi Y., Shiota Y., Iwata S., Nishino S., Yoshida A., Ohtori S., Kawai A., Kondo T.
Establishment and characterization of NCC-GCTB14-C1 and NCC-GCTB15-C1: two novel patient-derived cell lines of giant cell tumor of bone.
Hum. Cell 38:20.1-20.8(2025)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1