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Cellosaurus NCC-GCTB10-C1 (CVCL_E6MF)

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Cell line name NCC-GCTB10-C1
Accession CVCL_E6MF
Resource Identification Initiative To cite this cell line use: NCC-GCTB10-C1 (RRID:CVCL_E6MF)
Comments Part of: NCC sarcoma cell line panel.
Population: Japanese.
Senescence: It is possible that this cell line is not immortal and has a finite life span (personal communication of Kondo, Tadashi).
Doubling time: ~41.7 hours (PubMed=39653987).
Omics: Phenotyping; Drug screening.
Derived from site: In situ; Bone, proximal tibia; UBERON=UBERON_0008772.
Sequence variations
  • Mutation; HGNC; HGNC:4764; H3-3A; Simple; p.Gly35Trp (c.103G>T) (G34W); Zygosity=Heterozygous (PubMed=39653987).
Disease Malignancy in giant cell tumor of bone (NCIt: C4304)
Giant cell tumor of bone (ORDO: Orphanet_363976)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 27Y
Category Cancer cell line
STR profile Source(s): PubMed=39653987

Markers:
AmelogeninX,Y
CSF1PO12
D5S8189,10
D7S82011
D13S31710,11
D16S53910,14
D21S1130,31.2
TH016,9
TPOX8,11
vWA16,18

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Publications

PubMed=39653987; DOI=10.1007/s13577-024-01153-z
Yuki Adachi, Rei Noguchi, Julia Osaki, Takuya Ono, Taro Akiyama, Hiroya Kondo, Eisuke Kobayashi, Naoki Kojima, Akihiko Yoshida, Hideki Yokoo, Akira Kawai, Tadashi Kondo;
Establishment and characterization of NCC-GCTB10-C1: a novel cell line derived from a patient with recurrent giant cell tumor of bone.
Hum. Cell 38:29.1-29.11(2025)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1