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Cellosaurus ImHumAdrenal (CVCL_E6M0)

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Cell line name ImHumAdrenal
Accession CVCL_E6M0
Resource Identification Initiative To cite this cell line use: ImHumAdrenal (RRID:CVCL_E6M0)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Donor information: Established from a donor that underwenttumor nephrectomy for renal carcinoma (PubMed=24063979).
Derived from site: In situ; Adrenal gland; UBERON=UBERON_0002369.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=24063979; DOI=10.1016/j.jsbmb.2013.09.007
Pascal Werminghaus, Matthias Haase, Peter J. Hornsby, Sven Schinner, Matthias Schott, Ludwik Kazimierz Malendowicz, Bernhard J. Lammers, Peter E. Goretzki, Volker Muller-Mattheis, Markus Giessing, Holger Sven Willenberg;
Hedgehog-signaling is upregulated in non-producing human adrenal adenomas and antagonism of hedgehog-signaling inhibits proliferation of NCI-H295R cells and an immortalized primary human adrenal cell line.
J. Steroid Biochem. Mol. Biol. 139:7-15(2014)

Cross-references
Cell line collections (Providers) ABM; T0621
Entry history
Entry creation10-Apr-2025
Last entry update14-Aug-2025
Version number2