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Cellosaurus CUTO-37 ROS1 p.G2032R (CVCL_E6JA)

[Text version]
Cell line name CUTO-37 ROS1 p.G2032R
Accession CVCL_E6JA
Resource Identification Initiative To cite this cell line use: CUTO-37 ROS1 p.G2032R (RRID:CVCL_E6JA)
Comments Characteristics: The ROS1 mutation introduced is most prevalent among patients presenting relapsed disease. Sows significant resistance to ceritinib, crizotinib, entrectinib, lorlatinib and repotrectinib (DOI=10.63028/10067/2105480151162165141).
Sequence variations
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_C8T3 (CUTO-37)
Category Cancer cell line
Publications

DOI=10.63028/10067/2105480151162165141
Terrones M.
Profiling targeted therapy responses in ROS1+ non-small cell lung cancer using genomically engineered patient-derived cell lines.
Thesis PhD (2024); University of Antwerp; Antwerp; Belgium

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1