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Cellosaurus BT1160 (CVCL_E6G6)

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Cell line name BT1160
Synonyms CCLF-KL1066; CCLF_KL1066; CPDM_0103X
Accession CVCL_E6G6
Resource Identification Initiative To cite this cell line use: BT1160 (RRID:CVCL_E6G6)
Comments Part of: Cancer Cell Line Factory (CCLF) cell models.
Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
Population: Caucasian.
Characteristics: Can grow as a neurosphere (PubMed=34610309).
Omics: Genomics; Whole genome sequencing; Low read coverage.
Derived from site: In situ; Brain, left frontal cortex; UBERON=UBERON_0001870.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Leu (c.638G>T); ClinVar=VCV000376650; Zygosity=Unspecified (CPDM=CPDM_0103X).
Disease Astrocytoma, IDH-mutant, grade 4 (NCIt: C167335)
Diffuse astrocytoma (ORDO: Orphanet_251595)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 11Y
Category Cancer cell line
Web pages Provider; CPDM; CPDM_0103X; https://docs.google.com/spreadsheets/d/1sxAPF3p6xK2h01zaiQ1ExCWwzhxeZ-oDLN3s3LeJq98/edit?usp=sharing
Publications

PubMed=34610309; DOI=10.1016/j.celrep.2021.109788
Max A. Stockslager, Seth Malinowski, Mehdi Touat, Jennifer C. Yoon, Jack Geduldig, Mahnoor Mirza, Annette Sunhi Kim, Patrick Yung-Chih Wen, Kin-Hoe Chow, Keith Lloyd Ligon, Scott R. Manalis;
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
Cell Rep. 37:109788.1-109788.12(2021)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1