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Cellosaurus BT632 (CVCL_E6FS)

[Text version]
Cell line name BT632
Synonyms Ag1052; CPDM_0098X
Accession CVCL_E6FS
Resource Identification Initiative To cite this cell line use: BT632 (RRID:CVCL_E6FS)
Comments Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
Population: Caucasian.
Characteristics: Can grow as a neurosphere (PubMed=34610309).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Brain, right frontal cortex; UBERON=UBERON_0001870.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp53Ter (c.159G>A); ClinVar=VCV000420659; Zygosity=Unspecified (CPDM=CPDM_0098X).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg342Ter (c.1024C>T); ClinVar=VCV000182970; Zygosity=Unspecified (CPDM=CPDM_0098X).
Disease Glioblastoma, IDH-wildtype (NCIt: C39750)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 66Y
Category Cancer cell line
Web pages Provider; CPDM; CPDM_0098X; https://docs.google.com/spreadsheets/d/1sxAPF3p6xK2h01zaiQ1ExCWwzhxeZ-oDLN3s3LeJq98/edit?usp=sharing
Publications

PubMed=34610309; DOI=10.1016/j.celrep.2021.109788
Stockslager M.A., Malinowski S., Touat M., Yoon J.C., Geduldig J., Mirza M., Kim A.S., Wen P.Y.-C., Chow K.-H., Ligon K.L., Manalis S.R.
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
Cell Rep. 37:109788.1-109788.12(2021)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1