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Cellosaurus BT519 (CVCL_E6FN)

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Cell line name BT519
Synonyms CCLF-KL1256; CCLF_KL1256; CPDM_1331X
Accession CVCL_E6FN
Resource Identification Initiative To cite this cell line use: BT519 (RRID:CVCL_E6FN)
Comments Part of: Cancer Cell Line Factory (CCLF) cell models.
Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel.
Characteristics: Can grow as a neurosphere (PubMed=34610309).
Omics: Genomics; Whole genome sequencing; Low read coverage.
Derived from site: In situ; Brain, left occipital lobe; UBERON=UBERON_0002806.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Unspecified (CPDM=CPDM_1331X).
Disease Glioblastoma, IDH-wildtype (NCIt: C39750)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 50Y
Category Cancer cell line
Web pages Provider; CPDM; CPDM_1331X; https://docs.google.com/spreadsheets/d/1sxAPF3p6xK2h01zaiQ1ExCWwzhxeZ-oDLN3s3LeJq98/edit?usp=sharing
Publications

PubMed=34610309; DOI=10.1016/j.celrep.2021.109788
Max A. Stockslager, Seth Malinowski, Mehdi Touat, Jennifer C. Yoon, Jack Geduldig, Mahnoor Mirza, Annette Sunhi Kim, Patrick Yung-Chih Wen, Kin-Hoe Chow, Keith Lloyd Ligon, Scott R. Manalis;
Functional drug susceptibility testing using single-cell mass predicts treatment outcome in patient-derived cancer neurosphere models.
Cell Rep. 37:109788.1-109788.12(2021)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1