Cellosaurus cell line BT237 (CVCL

Entry history
Cell line name	BT237
Accession	CVCL_E6FF
Resource Identification Initiative	To cite this cell line use: BT237 (RRID:CVCL_E6FF)
Comments	Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel. Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132His (c.395G>A); ClinVar=VCV000156444; Zygosity=Unspecified (PubMed=22343896).
Disease	Anaplastic oligodendroglioma (NCIt: C4326) Anaplastic oligodendroglioma (ORDO: Orphanet_251630)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=22343896; DOI=10.1038/nature10898; PMCID=PMC3656605 Koivunen P., Lee S., Duncan C.G., Lopez G.Y., Lu G., Ramkissoon S.H., Losman J.-A., Joensuu P., Bergmann U., Gross S., Travins J., Weiss S., Looper R.E., Ligon K.L., Verhaak R.G.W., Yan H., Kaelin W.G. Jr. Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature 483:484-488(2012)
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1