Cellosaurus cell line BT138 (CVCL

Cellosaurus BT138 (CVCL_E6EX)

Entry history
Cell line name	BT138
Synonyms	CPDM_0814X
Accession	CVCL_E6EX
Resource Identification Initiative	To cite this cell line use: BT138 (RRID:CVCL_E6EX)
Comments	Part of: Center for Patient Derived Models (CPDM) at Dana-Farber Cancer Institute cell line panel. Population: Caucasian. Omics: Genomics; Whole exome sequencing. Omics: Genomics; Whole genome sequencing; Low read coverage. Omics: Transcriptomics; RNAseq. Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations	Mutation; HGNC; HGNC:5382; IDH1; Simple; p.Arg132His (c.395G>A); ClinVar=VCV000156444; Zygosity=Unspecified (PubMed=22343896).
Disease	Anaplastic oligodendroglioma (NCIt: C4326) Anaplastic oligodendroglioma (ORDO: Orphanet_251630)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	50Y
Category	Cancer cell line
Web pages	Provider; CPDM; CPDM_0814X; https://docs.google.com/spreadsheets/d/1sxAPF3p6xK2h01zaiQ1ExCWwzhxeZ-oDLN3s3LeJq98/edit?usp=sharing
Publications	PubMed=22343896; DOI=10.1038/nature10898; PMCID=PMC3656605 Peppi Koivunen, Sungwoo Lee, Christopher G. Duncan, Giselle Yvette Lopez, Gang Lu, Shakti H. Ramkissoon, Julie-Aurore Losman, Paivi Joensuu, Ulrich Bergmann, Stefan Gross, Jeremy Travins ...Show all 17 authors... , Samuel Weiss, Ryan E. Looper, Keith Lloyd Ligon, Roel G.W. Verhaak, Hai Yan, William G. Kaelin Jr.; Show fewer authors Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature 483:484-488(2012)
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1