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Cellosaurus BEAS-2B-CSC A (CVCL_E6CX)

[Text version]
Cell line name BEAS-2B-CSC A
Accession CVCL_E6CX
Resource Identification Initiative To cite this cell line use: BEAS-2B-CSC A (RRID:CVCL_E6CX)
Comments Characteristics: Very tumorigenic. Derived from xenografts produced by the parent cell line grown in deepithelialized rat tracheas that were subcutaneously transplanted into athymic nude mice and exposed to beeswax pellets containing cigarette smoke condensate (CSC) (PubMed=1323115).
Transformant: Ad12-SV40 hybrid virus.
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0168 (BEAS-2B)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

PubMed=1323115; DOI=10.1073/pnas.89.15.6693; PMCID=PMC49569
Klein-Szanto A.J.P., Iizasa T., Momiki S., Garcia de Palazzo I.E., Caamano J., Metcalf R.A., Welsh J.A., Harris C.C.
A tobacco-specific N-nitrosamine or cigarette smoke condensate causes neoplastic transformation of xenotransplanted human bronchial epithelial cells.
Proc. Natl. Acad. Sci. U.S.A. 89:6693-6697(1992)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1