Cellosaurus logo
expasy logo

Cellosaurus iMMEC WTA (CVCL_E6BX)

[Text version]
Cell line name iMMEC WTA
Synonyms immortalized Mouse Mammary Epithelial Cell line WTA
Accession CVCL_E6BX
Resource Identification Initiative To cite this cell line use: iMMEC WTA (RRID:CVCL_E6BX)
Comments Doubling time: 40-50 hours (ABM=T0451).
Genetic integration: Method=Transfection; Gene=MGI; MGI:98834; Trp53 (Note=With p.Leu14_Lys302del = p53DD).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03255; Adenovirus 5 E1A protein.
Transformant: NCBI_TaxID; 28285; Adenovirus 5 (Note=E1A).
Derived from site: In situ; Mammary gland; UBERON=UBERON_0001911.
Cell type: Epithelial cell of mammary gland; CL=CL_0002327.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_E6CC (iMMEC WTA-LC3)CVCL_E6C9 (iMMEC WTA.A5)CVCL_E6CA (iMMEC WTA.A7)
CVCL_E6C3 (iMMEC WTA.B1)CVCL_E6C4 (iMMEC WTA.B4)CVCL_E6CH (iMMEC WTA.H2)
CVCL_E6CI (iMMEC WTA.H3)CVCL_E6CF (iMMEC WTA.R3)CVCL_E6CG (iMMEC WTA.R5)
CVCL_E6C1 (iMMEC WTA.V)
Sex of cell Female
Age at sampling 6-8W
Category Transformed cell line
Publications

PubMed=17606641; DOI=10.1101/gad.1565707; PMCID=PMC1899472
Karantza-Wadsworth V., Patel S., Kravchuk O., Chen G.-H., Mathew R., Jin S.-K., White E.
Autophagy mitigates metabolic stress and genome damage in mammary tumorigenesis.
Genes Dev. 21:1621-1635(2007)

PubMed=18603116; DOI=10.1016/S0076-6879(08)01604-2; PMCID=PMC2857708
Karantza-Wadsworth V., White E.
A mouse mammary epithelial cell model to identify molecular mechanisms regulating breast cancer progression.
Methods Enzymol. 446:61-76(2008)

Cross-references
Cell line collections (Providers) ABM; T0451
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1