Cellosaurus MC38-hPD-L1-hCD47-LZ (CVCL_E6BK)
| Cell line name | MC38-hPD-L1-hCD47-LZ |
|---|---|
| Synonyms | genO-MC38-hPD-L1-hCD47-LZ |
| Accession | CVCL_E6BK |
| Resource Identification Initiative | To cite this cell line use: MC38-hPD-L1-hCD47-LZ (RRID:CVCL_E6BK) |
| Comments | Characteristics: Using CRISPR/Cas9 a construct containing a dual fusion reporter luciferase-ZsGreen (LZ) was introduced in one allele of the Rosa2 safe harbor locus (genOway). Knockout cell: Method=CRISPR/Cas9; MGI; MGI:1926446; Cd274. Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; W8LAG; ZsGreen (Note=FP506, green fluorescent protein derived from Zoanthus sp). Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:17635; CD274. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:1682; CD47. Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3430; ERBB2. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Transformant: ChEBI; CHEBI_73755; 1,2-dimethylhydrazine (DMH). Derived from site: In situ; Colon; UBERON=UBERON_0001155. |
| Disease | Mouse colon adenocarcinoma (NCIt: C120044) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6. |
| Hierarchy | Parent: CVCL_B7Q0 (MC38-hPD-L1-LZ) |
| Sex of cell | Female |
| Age at sampling | Age unspecified |
| Category | Cancer cell line |
| Web pages | Provider; genOway; -; https://www.genoway.com/product/catalog/mc38-pd-l1-cd47-lz |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 27-Nov-2025 |
| Version number | 3 |