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Cellosaurus CI-huEGC (CVCL_E6BG)

[Text version]
Cell line name CI-huEGC
Synonyms CIK
Accession CVCL_E6BG
Resource Identification Initiative To cite this cell line use: CI-huEGC (RRID:CVCL_E6BG)
Comments Characteristics: Transduced with a lentiviral library consisting of 33 genes, some of which are retained in the immortalized cell line (CI-SCREEN) (PubMed=37153631).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:5360; ID1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:7553; MYC.
Genetic integration: Method=Transduction; Gene=MGI; MGI:88174; Bmi1.
Genetic integration: Method=Transduction; Gene=MGI; MGI:1919200; Nanog.
Genetic integration: Method=Transduction; Gene=MGI; MGI:99187; Zfp42.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=Hepatitis C virus core protein.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Colon, myenteric nerve plexus; UBERON=UBERON_8410058.
Cell type: Enteric glial cell; CL=CL_4040002.
HLA typing Source: PubMed=37153631
Class I
HLA-AA*01:01,30:01
HLA-BB*07:02,08:01
HLA-CC*07:01,12:03
Class II
HLA-DQDQA1*01:02,01:03
DQB1*06:02,06:03
HLA-DRDRB1*13:01,15:01
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 75Y
Category Transformed cell line
STR profile Source(s): InSCREENeX=INS-CI-1030

Markers:
AmelogeninX
CSF1PO11,12
D2S133817,19
D3S135817,18
D5S81811,13
D7S82011,13
D8S117913,14
D13S31711,14
D16S53912,13
D18S5113,14
D19S43315
D21S1130,32.2
FGA21
TH016,8
TPOX8
vWA17

Run an STR similarity search on this cell line
Web pages Provider; InSCREENeX; INS-CI-1030; https://www.inscreenex.de/product/ci-huegc/
Publications

PubMed=37153631; DOI=10.3389/fncel.2023.1170309; PMCID=PMC10158601
Lisa Zanoletti, Aurora Valdata, Kristina Nehlsen, Pawan Faris, Claudio Casali, Rosalia Cacciatore, Ilaria Sbarsi, Francesca Carriero, Davide Arfini, Lies van Baarle, Veronica De Simone ...Show all 19 authors... , Giulia Barbieri, Elena Raimondi, Tobias May, Francesco Moccia, Mauro Bozzola, Gianluca Matteoli, Sergio Comincini, Federico Manai; Show fewer authors
Cytological, molecular, cytogenetic, and physiological characterization of a novel immortalized human enteric glial cell line.
Front. Cell. Neurosci. 17:1170309.1-1170309.16(2023)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1