Cellosaurus KTRC SIX2:CreERT2 (CVCL_E5YY)
| Cell line name | KTRC SIX2:CreERT2 | |
|---|---|---|
| Synonyms | Kidney Translational Research Center SIX2:CreERT2 iPSC | |
| Accession | CVCL_E5YY | |
| Resource Identification Initiative | To cite this cell line use: KTRC SIX2:CreERT2 (RRID:CVCL_E5YY) | |
| Comments | Population: Caucasian. Characteristics: Using CRISPR/Cas9 a T2A-CreERT2 construct has been inserted at the C-terminal of both alleles of SIX2 mCherry (PubMed=31492807). Genetic integration: Method=CRISPR/Cas9; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2). Genetic integration: Method=CRISPR/Cas9; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2). Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471. Cell type: Fibroblast of foreskin; CL=CL_1001608. | |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | |
| Hierarchy | Parent: CVCL_2769 (CCD-1112Sk) Children:
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| Sex of cell | Male | |
| Age at sampling | <1M | |
| Category | Induced pluripotent stem cell | |
| Web pages | Provider; KTRC; -; https://www.atlas-d2k.org/chaise/record/#2/Cell_Line:Reporter_Cell_Line/RID=16-E08P | |
| Publications | PubMed=31492807; DOI=10.1681/ASN.2019030303; PMCID=PMC6779359 | |
| Entry history | ||
| Entry creation | 10-Apr-2025 | |
| Last entry update | 10-Apr-2025 | |
| Version number | 1 | |