Cellosaurus KTRC SIX2:EGFP/CITED1:mCherry (CVCL_E5VQ)
| Cell line name | KTRC SIX2:EGFP/CITED1:mCherry |
|---|---|
| Synonyms | Kidney Translational Research Center SIX2:EGFP/CITED1:mCherry iPSC |
| Accession | CVCL_E5VQ |
| Resource Identification Initiative | To cite this cell line use: KTRC SIX2:EGFP/CITED1:mCherry (RRID:CVCL_E5VQ) |
| Comments | Population: Caucasian. Characteristics: Identifies mesenchymal nephron progenitors (NPs), early nephron populations (PubMed=31492807). Characteristics: Using CRISPR/Cas9 CITED1 has been endogenously tagged at the C-terminal of its single allele with mCherry and SIX2 has been endogenously tagged at the C-terminal of both alleles with EGFP (PubMed=31492807). Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=CRISPR/Cas9; Gene=FPbase; ZERB6; mCherry (Note=Red fluorescent protein derived from drFP583 (dsRed)). Derived from site: In situ; Foreskin, skin; UBERON=UBERON_0001471. Cell type: Fibroblast of foreskin; CL=CL_1001608. |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_VU01 (KTRC SIX2:EGFP) |
| Sex of cell | Male |
| Age at sampling | <1M |
| Category | Induced pluripotent stem cell |
| Web pages | Provider; KTRC; -; https://www.atlas-d2k.org/chaise/record/#2/Cell_Line:Reporter_Cell_Line/RID=14-3QDR |
| Publications | PubMed=31492807; DOI=10.1681/ASN.2019030303; PMCID=PMC6779359 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 10-Apr-2025 |
| Version number | 1 |