Cellosaurus OAiAC (CVCL_E5VI)
| Cell line name | OAiAC |
|---|---|
| Synonyms | OA iAC; OsteoArthritic immortalized Articular Chondrocytes |
| Accession | CVCL_E5VI |
| Resource Identification Initiative | To cite this cell line use: OAiAC (RRID:CVCL_E5VI) |
| Comments | Genetic integration: Method=Transduction; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT. Genetic integration: Method=Transduction; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR). Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Genetic integration: Method=Transduction; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR). Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Donor information: Established from an osteoarthritic patient that had a hip fracture (PubMed=36647698). Derived from site: In situ; Femoral head, cartilage; UBERON=UBERON_8480062. Cell type: Chondrocyte; CL=CL_0000138. |
| Disease | Osteoarthritis (NCIt: C3293) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Sex of cell | Male |
| Age at sampling | 88Y |
| Category | Transformed cell line |
| Publications | PubMed=36647698; DOI=10.1302/2046-3758.121.BJR-2022-0207.R1; PMCID=PMC9872042 |
| Cross-references | |
| Cell line collections (Providers) | ABM; T0385 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 14-Aug-2025 |
| Version number | 2 |