Cellosaurus UPPL1595 (CVCL_E5UM)
| Cell line name | UPPL1595 |
|---|---|
| Accession | CVCL_E5UM |
| Resource Identification Initiative | To cite this cell line use: UPPL1595 (RRID:CVCL_E5UM) |
| Comments | From: Kim, William Y.; University of North Carolina at Chapel Hill; Chapel Hill; USA. Characteristics: Displays a similar expression profiles to luminal-like molecular subtype bladder cancers in humans (ABM=T8072). Knockout cell: Method=KO mouse; MGI; MGI:109583; Pten. Knockout cell: Method=KO mouse; MGI; MGI:98834; Trp53. Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg. Fused to Cre = CreERT2). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1 = CreERT2). Derived from site: In situ; Urinary bladder; UBERON=UBERON_0001255. Cell type: Urothelial cell; CL=CL_0000731. |
| Disease | Mouse bladder transitional cell carcinoma (NCIt: C25823) |
| Species of origin | Mus musculus (Mouse)
(NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 Upk3a-CreERT2, Trp53L/L, PtenL/L, Rosa26LSL-Luc transgenic. |
| Sex of cell | Sex unspecified |
| Age at sampling | Age unspecified |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections (Providers) | ABM; T8072 |
| Entry history | |
| Entry creation | 10-Apr-2025 |
| Last entry update | 10-Apr-2025 |
| Version number | 1 |