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Cellosaurus M213-2O (CVCL_E5TG)

[Text version]
Cell line name M213-2O
Accession CVCL_E5TG
Resource Identification Initiative To cite this cell line use: M213-2O (RRID:CVCL_E5TG)
Comments Characteristics: Has GABAgeric properties with multiple nucleoli, and no contact inhibition features. At the permissive temperature (33 Celsius) expresses glutamate decarboxylase (GAD). At the nonpermissive temperature (39.3 Celsius) also expresses MAP2 (PubMed=8287936).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Embryonic brain, forebrain, striatum; UBERON=UBERON_0006240+UBERON_0002435.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Sprague Dawley; RS=RS_0000681.
Sex of cell Sex unspecified
Age at sampling 14FD
Category Transformed cell line
Publications

PubMed=8287936; DOI=10.1006/exnr.1993.1213
Giordano M., Takashima H., Herranz A., Poltorak M., Geller H.M., Marone M., Freed W.J.
Immortalized GABAergic cell lines derived from rat striatum using a temperature-sensitive allele of the SV40 large T antigen.
Exp. Neurol. 124:395-400(1993)

Cross-references
Cell line collections (Providers) ABM; T0356
Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1