Cellosaurus cell line SF295 MX1500 (CVCL

Cross-references
Cell line name	SF295 MX1500
Accession	CVCL_E5T6
Resource Identification Initiative	To cite this cell line use: SF295 MX1500 (RRID:CVCL_E5T6)
Comments	Population: Caucasian. Characteristics: Resistant to 1500 nM of mitoxantrone (ABM=T8043). Selected for resistance to: ChEBI; CHEBI_50729; Mitoxantrone. Derived from site: In situ; Brain, left temporal lobe; UBERON=UBERON_0002808.
Sequence variations	Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg233Ter (c.697C>T); ClinVar=VCV000007813; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Gln (c.743G>A); ClinVar=VCV000012356; Zygosity=Homozygous (from parent cell line).
Disease	Glioblastoma (NCIt: C3058) Glioblastoma (ORDO: Orphanet_360)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1690 (SF295)
Sex of cell	Female
Age at sampling	67Y
Category	Cancer cell line
Cell line collections (Providers)	ABM; T8043
Entry history
Entry creation	10-Apr-2025
Last entry update	10-Apr-2025
Version number	1