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Cellosaurus 5E6-2E7 (CVCL_E5NE)

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Cell line name 5E6-2E7
Accession CVCL_E5NE
Resource Identification Initiative To cite this cell line use: 5E6-2E7 (RRID:CVCL_E5NE)
Comments Monoclonal antibody isotype: IgG3, kappa.
Monoclonal antibody target: ChEBI; CHEBI_61818; N-acetyl-alpha-neuraminyl-(2->6)-N-acetyl-alpha-D-galactosamine (CD175s; Sialyl-Tn) (Note=O-linked to serine or threonine).
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Category Hybridoma
Publications

PubMed=28281872; DOI=10.1080/19420862.2017.1290752; PMCID=PMC5419082
Jillian M. Prendergast, Ana Paula Galvao da Silva, David A. Eavarone, Darius Ghaderi, Mai Zhang, Dane Brady, Joan Wicks, Julie DeSander, Jeffrey Behrens, Bo R. Rueda;
Novel anti-sialyl-Tn monoclonal antibodies and antibody-drug conjugates demonstrate tumor specificity and anti-tumor activity.
MAbs 9:615-627(2017)

Patent=US9879087
Julie DeSander, Jeffrey Behrens, Alexey Alexandrovich Lugovskoy;
Glycan-interacting compounds and methods of use.
Patent number US9879087, 30-Jan-2018

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1