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Cellosaurus HEK293 Kv1.5-12PA (CVCL_E5JJ)

[Text version]
Cell line name HEK293 Kv1.5-12PA
Synonyms Kv1.5-12PA-HEK
Accession CVCL_E5JJ
Resource Identification Initiative To cite this cell line use: HEK293 Kv1.5-12PA (RRID:CVCL_E5JJ)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6224; KCNA5 (Note=With all 12 Pro from AA285 to AA317 mutated to Ala).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0045 (HEK293)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=32122972; DOI=10.1074/jbc.RA119.011302; PMCID=PMC7136002
Milton A.O., Wang T.-Z., Li W.-T., Guo J., Zhang S.-T.
Mechanical stretch increases Kv1.5 current through an interaction between the S1-S2 linker and N-terminus of the channel.
J. Biol. Chem. 295:4723-4732(2020)

Entry history
Entry creation10-Apr-2025
Last entry update10-Apr-2025
Version number1