Cellosaurus cell line CBC3T-6 (CVCL

Cellosaurus CBC3T-6 (CVCL_E5HL)

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Cell line name

CBC3T-6

Accession

CVCL_E5HL

Resource Identification Initiative

To cite this cell line use: CBC3T-6 (RRID:CVCL_E5HL)

Comments

Population: Chinese.
Characteristics: Highly tumorigenic (PubMed=39613883).
Doubling time: ~50 hours (PubMed=39613883).
Karyotypic information: Nearly triploid (PubMed=39613883).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Extrahepatic bile duct; UBERON=UBERON_0003703.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=39613883).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Glu336Ter (c.1006G>T); Zygosity=Unspecified (PubMed=39613883).

Disease

Distal cholangiocarcinoma (NCIt: C7976)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

44Y

Category

Cancer cell line

STR profile

Source(s): PubMed=39613883

Markers:

Amelogenin	X
CSF1PO	10
D2S441	11,15
D2S1338	22,23
D3S1358	15,16
D5S818	11
D6S1043	19
D7S820	11,13
D8S1179	12
D12S391	20,22
D13S317	8,10
D16S539	9,11
D18S51	13.3,14.3
D19S433	14,14.2
D21S11	30,31
FGA	21,25
Penta D	11,15
Penta E	12,14
TH01	8,9.3
TPOX	9,11
vWA	14

Publications

PubMed=39613883; DOI=10.1038/s41598-024-81392-0; PMCID=PMC11607416
Ming-Zhen Bai, Ruo-Shui Wang, Chong-Fei Huang, Ru-Yang Zhong, Ning-Zu Jiang, Wen-Kang Fu, Ning-Ning Mi, Long Gao, Yu-Yao Jin, Hai-Dong Ma, Jie Cao ...Show all 19 authors... , Hai-Ying Yu, Qiang Jing, Chao Zhang, Ping Yue, Yong Zhang, Yan-Yan Lin, Heng-Wei Zhang, Wen-Bo Meng; Show fewer authors
Biological and genetic characterization of a newly established human primary multidrug-resistant distal cholangiocarcinoma cell line, CBC3T-6.
Sci. Rep. 14:29661.1-29661.12(2024)

Entry history

Entry creation

10-Apr-2025

Last entry update

10-Apr-2025

Version number