Cellosaurus cell line SW480 EGFP-lamin A clone 1B4 (CVCL

Cross-references
Cell line name	SW480 EGFP-lamin A clone 1B4
Synonyms	SW480 GFP-lamin A clone 1B4
Accession	CVCL_E5G5
Resource Identification Initiative	To cite this cell line use: SW480 EGFP-lamin A clone 1B4 (RRID:CVCL_E5G5)
Comments	Population: Caucasian. Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:6636; LMNA. Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations	Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).
Disease	Colon adenocarcinoma (NCIt: C4349)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0546 (SW480)
Sex of cell	Male
Age at sampling	51Y
Category	Cancer cell line
Cell line collections (Providers)	CancerTools; 162197
Entry history
Entry creation	10-Apr-2025
Last entry update	14-Aug-2025
Version number	2