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Cellosaurus LIU-LSC-1 (CVCL_E5DZ)

[Text version]
Cell line name LIU-LSC-1
Accession CVCL_E5DZ
Resource Identification Initiative To cite this cell line use: LIU-LSC-1 (RRID:CVCL_E5DZ)
Comments Population: Chinese.
Characteristics: Highly tumorigenic. Has a dysregulated activity of mTORC1 (PubMed=36438491).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Cell type: Epithelial cell; CL=CL_0000066.
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_E5E0 (LIU-LSC-1 ITGA5 KO1)CVCL_E5E1 (LIU-LSC-1 ITGA5 KO2)
Sex of cell Male
Age at sampling 74Y
Category Cancer cell line
STR profile Source(s): PubMed=36438491

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133821,23
D3S135816
D5S81812
D6S104311,12
D7S8208,11
D8S117913,14
D12S39115,22
D13S3178
D16S53911
D18S5120
D19S43315.2,16.2
D21S1129
FGA23
Penta D13
Penta E16,22
TH018
TPOX8,11
vWA16

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Publications

PubMed=36438491; DOI=10.7150/thno.76232; PMCID=PMC9691358
Li D.-P., Sun A.-J., Zhang L., Ding Z., Yi F.-Z., Yang X., Wang Z.-X., Chen X., Liu W.-W., Liu S.-X., Shen H.-L., Miao M.-L., Zhang L., Liu P., Liu Y.-C., Su S.-H., Huang H.-L., Huang C., Hu Z.-D., Zhang H.-B., Zha X.-J., Liu Y.-H.
Elevated ITGA5 facilitates hyperactivated mTORC1-mediated progression of laryngeal squamous cell carcinoma via upregulation of EFNB2.
Theranostics 12:7431-7449(2022)

Entry history
Entry creation19-Dec-2024
Last entry update10-Apr-2025
Version number2