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Cellosaurus COX (CVCL_E534)

[Text version]
Cell line name COX
Accession CVCL_E534
Resource Identification Initiative To cite this cell line use: COX (RRID:CVCL_E534)
Comments Part of: 10th International Histocompatibility Workshop (10IHW) cell line panel.
Population: Caucasian.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: HLA class II peptidome analysis by proteomics.
Omics: MHC region genome.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.
HLA typing Source: IPD-IMGT/HLA=10429
Class I
HLA-AA*01:01:01:01
HLA-BB*08:01:01:01
HLA-CC*07:01:01:01
Class II
HLA-DPDPA1*01:03:01:03
DPB1*03:01:01
HLA-DQDQA1*05:01:01
DQB1*02:01:01
HLA-DRDRA*01:02
DRB1*03:01:01
DRB3*01:01:02:01

Source: PubMed=30844424
Class I
HLA-AA*01:01:01:01
HLA-BB*08:01:01:01
HLA-CC*07:01:01:01
Class II
HLA-DPDPA1*01:03:01:03
DPB1*03:01:01
HLA-DQDQA1*05:01:01:02
DQB1*02:01:01
HLA-DRDRB1*03:01:01
DRB3*01:01:02
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
Publications

DOI=10.1007/978-1-4612-3552-1_2
Yang S.Y., Milford E.L., Hammerling U., Dupont B.
Description of the reference panel of B-lymphoblastoid cell lines for factors of the HLA system: the B-cell line panel designed for the Tenth International Histocompatibility Workshop.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.11-19; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_4
Mickelson E.M., Reinsmoen N.L., Robbins F.-M., Hartzman R.J., Odum N., Svejgaard A., Farrell C., Honeyman M.C., Flomenberg N., Sell T.W., Eckels D.D.
HLA-Dw and HLA-DP typing of the reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.38-42; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_5
Yang S.Y.
Assignment of HLA-A and HLA-B antigens for the reference panel of B-lymphoblastoid cell lines determined by one-dimensional isoelectric focusing (lD-IEF) gel electrophoresis.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.43-44; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_6
Knowles R.W.
Assignment of HLA-class II alpha and beta chain 2-D gel patterns for the workshop reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.44-46; Springer; New York; USA (1989)

DOI=10.1007/978-1-4612-3552-1_7
Flomenberg N.
Assignment of T-cell-defined (TCD) HLA class II specificities for the reference panel of B-lymphoblastoid cell lines.
(In book chapter) Immunobiology of HLA. Volume I. Histocompatibility testing 1987; Dupont B. (eds.); pp.46-48; Springer; New York; USA (1989)

PubMed=8307784; DOI=10.1016/0198-8859(93)90514-2
Degli-Esposti M.A., Griffiths M.S.J., Daly L.N., Witt C.S., Simons M., Carcassi C., Albert E.D., Giphart M.J., Dawkins R.L.
Characterization of 4AOHW cell line panel including new data for the 10IHW panel.
Hum. Immunol. 38:3-16(1993)

PubMed=8813743; DOI=10.1111/j.1399-0039.1996.tb02596.x
Prasad V.K., Yang S.Y.
Allele assignment for HLA-A, -B, and -C genes to the Tenth International Histocompatibility Workshop cell lines.
Tissue Antigens 47:538-546(1996)

PubMed=15140828; DOI=10.1101/gr.2188104; PMCID=PMC419796
Stewart C.A., Horton R., Allcock R.J.N., Ashurst J.L., Atrazhev A.M., Coggill P., Dunham I., Forbes S., Halls K., Howson J.M.M., Humphray S.J., Hunt S., Mungall A.J., Osoegawa K., Palmer S., Roberts A.N., Rogers J., Sims S., Wang Y., Wilming L.G., Elliott J.F., de Jong P.J., Sawcer S., Todd J.A., Trowsdale J., Beck S.
Complete MHC haplotype sequencing for common disease gene mapping.
Genome Res. 14:1176-1187(2004)

PubMed=16440057; DOI=10.1371/journal.pgen.0020009; PMCID=PMC1331980
Traherne J.A., Horton R., Roberts A.N., Miretti M.M., Hurles M.E., Stewart C.A., Ashurst J.L., Atrazhev A.M., Coggill P., Palmer S., Almeida-King J., Sims S., Wilming L.G., Rogers J., de Jong P.J., Carrington M.N., Elliott J.F., Sawcer S., Todd J.A., Trowsdale J., Beck S.
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.
PLoS Genet. 2:E9-E9(2006)

PubMed=16702430; DOI=10.1534/genetics.106.057034; PMCID=PMC1526686
Shiina T., Ota M., Shimizu S., Katsuyama Y., Hashimoto N., Takasu M., Anzai T., Kulski J.K., Kikkawa E., Naruse T., Kimura N., Yanagiya K., Watanabe A., Hosomichi K., Kohara S., Iwamoto C., Umehara Y., Meyer A., Wanner V., Sano K., Macquin C., Ikeo K., Tokunaga K., Gojobori T., Inoko H., Bahram S.
Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity.
Genetics 173:1555-1570(2006)

PubMed=18193213; DOI=10.1007/s00251-007-0262-2; PMCID=PMC2206249
Horton R., Gibson R., Coggill P., Miretti M.M., Allcock R.J.N., Almeida-King J., Forbes S., Gilbert J.G.R., Halls K., Harrow J.L., Hart E., Howe K.L., Jackson D.K., Palmer S., Roberts A.N., Sims S., Stewart C.A., Traherne J.A., Trevanion S., Wilming L.G., Rogers J., de Jong P.J., Elliott J.F., Sawcer S., Todd J.A., Trowsdale J., Beck S.
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project.
Immunogenetics 60:1-18(2008)

PubMed=28360230; DOI=10.1101/gr.213538.116; PMCID=PMC5411776
Norman P.J., Norberg S.J., Guethlein L.A., Nemat-Gorgani N., Royce T., Wroblewski E.E., Dunn T., Mann T., Alicata C., Hollenbach J.A., Chang W.-H., Shults Won M., Gunderson K.L., Abi-Rached L., Ronaghi M., Parham P.
Sequences of 95 human MHC haplotypes reveal extreme coding variation in genes other than highly polymorphic HLA class I and II.
Genome Res. 27:813-823(2017)

PubMed=29171935; DOI=10.1111/tan.13184
Turner T.R., Hayhurst J.D., Hayward D.R., Bultitude W.P., Barker D.J., Robinson J., Madrigal J.A., Mayor N.P., Marsh S.G.E.
Single molecule real-time DNA sequencing of HLA genes at ultra-high resolution from 126 international HLA and immunogenetics workshop cell lines.
HLA 91:88-101(2018)

PubMed=30844424; DOI=10.1016/j.humimm.2019.03.001; PMCID=PMC6599558
Creary L.E., Guerra S.G., Chong W., Brown C.J., Turner T.R., Robinson J., Bultitude W.P., Mayor N.P., Marsh S.G.E., Saito K., Lam K., Duke J.L., Mosbruger T.L., Ferriola D., Monos D.S., Willis A., Askar M., Fischer G.F., Saw C.L., Ragoussis J., Petrek M., Serra-Pages C., Juan Otero M., Stavropoulos-Giokas C., Dinou A., Ameen R., Al Shemmari S., Spierings E., Gendzekhadze K., Morris G.P., Zhang Q.-H., Kashi Z., Hsu S., Gangavarapu S., Mallempati K.C., Yamamoto F., Osoegawa K., Vayntrub T., Chang C.-J., Hansen J.A., Fernandez-Vina M.A.
Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: report from the 17th International HLA and Immunogenetics Workshop.
Hum. Immunol. 80:449-460(2019)

Cross-references
Cell line collections (Providers) CLS; 302138
Cell line databases/resources dbMHC; 48733
IHW; IHW09022
IPD-IMGT/HLA; 10429
Encyclopedic resources Wikidata; Q54814358
Proteomic databases PRIDE; PXD017682
Entry history
Entry creation22-Oct-2012
Last entry update30-Jan-2024
Version number20