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Cellosaurus CCX.E10 (CVCL_E4II)

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Cell line name CCX.E10
Accession CVCL_E4II
Resource Identification Initiative To cite this cell line use: CCX.E10 (RRID:CVCL_E4II)
Comments Group: Bird cell line.
Group: Serum/protein free medium cell line.
Group: Vaccine production cell line.
From: Nuvonis Technologies GmbH; Vienna; Austria.
Biotechnology: Can be used for the manufacturing of the fusogenic oncolytic virus, rVSV-NDV, a recombinant vesicular stomatitis virus (VSV) backbone with fusogenic mutant glycoproteins of Newcastle disease virus (NDV) (PubMed=37584190).
Characteristics: Grows in suspension (Nuvonis).
Virology: When infected with Newcastle disease virus (NDV) produces high viral titers (CelloPub=CLPUB00780).
Doubling time: 0.8-1 day (Nuvonis).
Miscellaneous: Age at sampling from personal communication of Seipelt, Joachim.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Coturnix japonica (Japanese quail) (Coturnix coturnix japonica) (NCBI Taxonomy: 93934)
Originate from same individual CVCL_E4IH ! CCX.2C4
Sex of cell Sex unspecified
Age at sampling 12FD
Category Spontaneously immortalized cell line
Web pages Provider; Nuvonis; -; https://nuvonis.com/ccx-cell-line/
Publications

CLPUB00780
Hana Jug, Natalija Hosta, Mojca Tajnik Sbaizero, Ales Strancar, Daniela Marie Brodesser, Bianca Tisch, Theresa Heger, Markus Wolschek, Joachim Seipelt, Manfred Reiter;
Production and purification of Newcastle disease virus.
BioProcess Int. 21:17-20(2023)

PubMed=37584190; DOI=10.1002/bit.28530
Sven Gobel, Karim Enrique Jaen, Rita Patricio Fernandes, Manfred Reiter, Jennifer Altomonte, Udo Reichl, Yvonne Genzel;
Characterization of a quail suspension cell line for production of a fusogenic oncolytic virus.
Biotechnol. Bioeng. 120:3335-3346(2023)

Entry history
Entry creation19-Dec-2024
Last entry update10-Apr-2025
Version number2