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Cellosaurus EP2-15 (CVCL_E4CG)

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Cell line name EP2-15
Synonyms EP215
Accession CVCL_E4CG
Resource Identification Initiative To cite this cell line use: EP2-15 (RRID:CVCL_E4CG)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; HGNC:14294; SHANK3.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_E4CF (2242-5)
Sex of cell Male
Age at sampling Age unspecified
Category Induced pluripotent stem cell
Publications

PubMed=33558651; DOI=10.1038/s41380-021-01023-2; PMCID=PMC8349370
Simone Chiola, Kandy L. Napan, Yue-Qi Wang, Roman M. Lazarenko, Celeste J. Armstrong, Jun Cui, Aleksandr Shcheglovitov;
Defective AMPA-mediated synaptic transmission and morphology in human neurons with hemizygous SHANK3 deletion engrafted in mouse prefrontal cortex.
Mol. Psychiatry 26:4670-4686(2021)

PubMed=36202854; DOI=10.1038/s41467-022-33364-z; PMCID=PMC9537523
Yue-Qi Wang, Simone Chiola, Guang Yang, Chad Russell, Celeste J. Armstrong, Yuan-Yuan Wu, Jay G. Spampanato, Paisley Tarboton, H.M. Arif Ullah, Nicolas U. Edgar, Amelia N. Chang ...Show all 19 authors... , David A. Harmin, Vittoria Dickinson Bocchi, Elena Vezzoli, Dario Besusso, Jun Cui, Elena Cattaneo, Jan Kubanek, Aleksandr Shcheglovitov; Show fewer authors
Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes.
Nat. Commun. 13:5688.1-5688.25(2022)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1