Cellosaurus cell line ES-ZSS-1 (CVCL

Cellosaurus ES-ZSS-1 (CVCL_E4C6)

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Cell line name

ES-ZSS-1

Accession

CVCL_E4C6

Resource Identification Initiative

To cite this cell line use: ES-ZSS-1 (RRID:CVCL_E4C6)

Comments

Population: Chinese.
Characteristics: Established from a mice patient-derived xenograft (PubMed=39475964).
Doubling time: ~61 hours (PubMed=39475964).
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Abdominal wall, hypodermis; UBERON=UBERON_0003697+UBERON_0002072.

Sequence variations

Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1 (PubMed=39475964).
Mutation; HGNC; HGNC:11355; STAG2; Simple; p.Gln963Serfs; Zygosity=Unspecified (PubMed=39475964).

Disease

Extraskeletal Ewing sarcoma (NCIt: C7135)
Extraskeletal Ewing sarcoma (ORDO: Orphanet_370334)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Female

Age at sampling

40Y

Category

Cancer cell line

STR profile

Source(s): PubMed=39475964

Markers:

Amelogenin	X
CSF1PO	10,12
D5S818	9,11
D7S820	9,10
D13S317	8,10
D16S539	11,13
TH01	9
TPOX	8,9
vWA	16,17

Publications

PubMed=39475964; DOI=10.1007/s13577-024-01133-3
Chen-Lu Zhang, Meng-Ling Liu, Li-Juan Luan, Xi Guo, Yang You, Zhi-Ming Wang, Wei Li, Nan-Hang Lu, Ying-Yong Hou, Li-Li Lu, Wei-Qi Lu, Yu-Hong Zhou;
Establishment and characterization of a patient-derived metastatic extraskeletal Ewing sarcoma cell line ES-ZSS-1.
Hum. Cell 38:12.1-12.9(2025)

Entry history

Entry creation

19-Dec-2024

Last entry update

10-Apr-2025

Version number