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Cellosaurus Ma-Mel-144aI (CVCL_E4B4)

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Cell line name Ma-Mel-144aI
Synonyms Ma-Mel 144aI; MaMel-144a; MaMel144aI
Accession CVCL_E4B4
Resource Identification Initiative To cite this cell line use: Ma-Mel-144aI (RRID:CVCL_E4B4)
Comments Miscellaneous: Sex and age of donor from personal communication of Schadendorf, Dirk through Yeh, Iwei.
Miscellaneous: STR profile from personal communication of Yeh, Iwei.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Sequence variations
  • Mutation; HGNC; HGNC:6342; KIT; Simple; p.Ser476Ile (c.1427G>T); Zygosity=Heterozygous; Note=Activating mutation (PubMed=21595858).
Disease Acral lentiginous melanoma (NCIt: C4022)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133817
D3S135814,16
D5S81811
D7S82012
D8S117910
D13S31713
D16S53911
D18S5118,19
D19S43315
D21S1130
FGA22
Penta D10,14
Penta E7,17
TH019
TPOX9
vWA19

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Publications

PubMed=21595858; DOI=10.1111/j.1755-148X.2011.00870.x
Rui-Xia Liang, Andrea R. Wallace, Dirk Schadendorf, Brian P. Rubin;
The phosphatidyl inositol 3-kinase pathway is central to the pathogenesis of Kit-activated melanoma.
Pigment Cell Melanoma Res. 24:714-723(2011)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1