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Cellosaurus HSC 536 FANCC (CVCL_E3YF)

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Cell line name HSC 536 FANCC
Synonyms FA-C+C
Accession CVCL_E3YF
Resource Identification Initiative To cite this cell line use: HSC 536 FANCC (RRID:CVCL_E3YF)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3584; FANCC.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00557; Escherichia coli hygromycin-B 4-O-kinase (hph) (HygR).
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:3584; FANCC; Simple; p.Leu554Pro (c.1661T>C); ClinVar=VCV000012043; Zygosity=Unspecified (Coriell=GM13020).
Disease Fanconi anemia, complementation group C (NCIt: C125704)
Fanconi anemia (ORDO: Orphanet_84)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_G045 (HSC 536)
Sex of cell Male
Age at sampling 5Y
Category Transformed cell line
Publications

PubMed=14754601
Alan A. Clarke, Frances M. Gibson, Julie Scott, Nyree E. Myatt, Timothy R. Rutherford;
Fanconi's anemia cell lines show distinct mechanisms of cell death in response to mitomycin C or agonistic anti-Fas antibodies.
Haematologica 89:11-20(2004)

Entry history
Entry creation19-Dec-2024
Last entry update19-Dec-2024
Version number1