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Cellosaurus UAB-Pkd2 Ex15-WT/Pkd2 delta; CAGGcre; Sstr3GFP clone 8 (CVCL_E3Y7)

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Cell line name UAB-Pkd2 Ex15-WT/Pkd2 delta; CAGGcre; Sstr3GFP clone 8
Synonyms PKD2Ex15-WT/PKD2 delta; CAGGcre; sstr3GFP clone8
Accession CVCL_E3Y7
Resource Identification Initiative To cite this cell line use: UAB-Pkd2 Ex15-WT/Pkd2 delta; CAGGcre; Sstr3GFP clone 8 (RRID:CVCL_E3Y7)
Comments From: University of Alabama at Birmingham - Polycystic Kidney Disease center (UAB-PKD); Birmingham; USA.
Characteristics: In the donor mouse one allele of Pkd2 is floxed. Two transgene constructs expressing Sstr3:GFP and pCAGGCre-ER are also present (UAB-PKD).
Knockout cell: Method=KO mouse; MGI; MGI:1099818; Pkd2 (Note=1 of 2 alleles; floxed).
Genetic integration: Method=Transduction; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transgenic mouse; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:1352467; Esr1 (Note=Ligand binding domain; with p.Gly525Arg).
Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P06956; Escherichia phage P1 cre (Note=Fused to ligand domain of mouse Esr1).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Male
Age at sampling 1M
Category Transformed cell line
Entry history
Entry creation19-Dec-2024
Last entry update10-Apr-2025
Version number2